Research of high-dose amoxicillin in Helicobacter pylori therapy by increasing gastric PH value

Research of Esomeprazole 20 mg qid combined with high-dose amoxicillin as first-line Helicobacter pylori therapy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15007245

Enrollment

Unknown

Registered

2015-10-18

Start date

2015-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

1:esomeprazole 20mg qid+amoxicillin 0.75 qid

2:esomeprazole 20mg bid+ bismuth potassium citrate 220mg bid +amoxicillin1.0 bid +clarithromycin 0.5 bid

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Over 18 years old patients infected with helicobacter prlori.

Exclusion criteria

Exclusion criteria: pregnancy,breast-feed,serious diseases,malignancy ,the study drug allergy,severe ulcer bleeding or perforation,not the first time for helicobacter prlori eradication, taking PPIs or antibiotics within the past 4 weeks.

Design outcomes

Primary

Measure	Time frame
HP eradication rate;clarithromycin resistance;	—

Countries

China

Contacts

Public ContactCaiping Gao

gaocaip@126.com+86 17708130286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026