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Effect of Dexmedetomidine and sufentanil on the Quality of Postoperative Analgesia and POCD in Highly-nicotine Dependent Patients After Video assisted thoracic surgery:A CONSORT-Prospective, Randomized, Controlled Trial

Effect of Dexmedetomidine and sufentanil on the Quality of Postoperative Analgesia and POCD in Highly-nicotine Dependent Patients After Video assisted thoracic surgery:A CONSORT-Prospective, Randomized, Controlled Trial

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007229
Enrollment
Unknown
Registered
2015-10-17
Start date
2015-10-17
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain

Interventions

S group:sufentanil
D1 group:dexmedetomidine+sufentanil
D2 group:dexmedetomidine+sufentanil

Sponsors

Liaocheng People’s Hospital, Liaocheng,Shandong province
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 35 Years

Inclusion criteria

Inclusion criteria: Highly-nicotine (Fagerstrom Test of Nicotine Dependence (FTND) >=6) dependent patients; ASA II~III; Age: 35~65y; Patients undergoing video-assisted thoracic surgery.

Exclusion criteria

Exclusion criteria: Body mass index>30 kg/m2; Severe heart lung, liver kidney and other organ diseases; The use of antihypertensive drugs or beta adrenergic receptor blocker before surgery(>3 months); Be allergic to sufentanil or dexmedetomidine; A history of chronic pain and the long-term use of analgesic drugs (>3 months).

Design outcomes

Primary

MeasureTime frame
the scores of pain;Opioid consumption.;—

Secondary

MeasureTime frame
the scores of sedation;POCD;Adverse reactions;Hospitalization time, hospitalization expenses;Long term life quality;—

Countries

China

Contacts

Public ContactChunguang Ren
weiyichunguang@163.com+86 13561239696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026