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The effect of acupuncture on gastrointestinal disorder in patients underwent colorectal tumorectomy and its serum microRNA related mechanism

The effect of acupuncture on gastrointestinal disorder in patients underwent colorectal tumorectomy and its serum microRNA related mechanism

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007226
Enrollment
Unknown
Registered
2015-10-16
Start date
2015-10-16
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative gastrointestinal disorder

Interventions

acupuncture group:acupuncture
presurgery acupuncture group:presurgery acupuncture
control group:postoperative routine care

Sponsors

the First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. histologically proven colorectal cancer (i.e. via colonoscopy and/or any other method) with a resectable primary tumour in situ and with or without unresectable distant metastases requiring radiotherapy or chemotherapy; 2. performance status of 0 or 1 based on the Eastern Cooperative Oncology Group (ECOG) criteria; 3. aged 30-75; 4. Willing to accept the whole treatment course and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. rejection of receiving surgery; 2. acute colonic obstruction or perforation; emergency operation; 3. previous or secondary malignancy; 4. previous operation with vagotomy; enterostomy; 5. first exhaust or defecation within 16h postoperatively; 6. preexisting severe cardiovascular, hepatic, renal, hematological, immunologic, mental disease, hyper/hypothyroidism, intestinal parasitic, spinal cord injury; uncontrolled infections requiring systemic therapy; uncontrollable diabetes, hypertension (values>=150/100mmHg); 7. continuous treatment with adrenoceptor stimulating or blocking agents, cholinergic or anticholinergic agents; 8. obvious postoperative complications such as anastomotic leakage or intra-abdominal sepsis; 9. pregnancy, lactation; 10. incapability to continue treatments in this study or application of other therapies like enemas or laxatives to improve gastrointestinal motility due to disease evolution.

Design outcomes

Primary

MeasureTime frame
first exsufflation time;first defaecation time;time for ?rst tolerance of solid food;serum microRNA;tissue microRNA;

Countries

China

Contacts

Public ContactYuanqing
yuanqing1005@126.com+86 13902211008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026