Cervical Cancer
Conditions
Interventions
IMRT-Group:Using IMRT technic
3DCRT-Group:Using 3DCRT technic
Sponsors
Cancer Hospital of Shantou University Medical College
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with cervical cancer confirmed by histology or cytology; 2. Patients with International Federation of Gynecology and Obstetrics (FIGO 2009) stage II staged by at least one gynecological oncologist (associate chief physician or higher); 3. Patients who had no prior anti-cancer treatment; 4. Patients who have at least one measurable lesion (at least 10mm*10mm in MRI scan of pelvis); 5. Aged 18 to 70 years; 6. ECOG performance status 0 - 2; 7. Weight >=40KG; 8. WBC >=4.0*10^9/L, Hemoglobin>=90g/L, Platelets >=100.0*10^9/L; Bilirubin <=ULN; ALT and AST and ALP<=2.5*ULN; BUN <=1.5*ULN; Creatinine<=1.5*ULN; 9. Signed study-specific informed consent.
Exclusion criteria
Exclusion criteria: 1. Any previous chemotherapy, radiotherapy or surgery for this tumour; 2. Para-aortic nodal involvement or evidence of distant metastasis; 3. Patients who have severe uncontrolled internal diseases or acute infection; 4. Patients who are pregnant or lactating; 5. Patients who did not sign study-specific informed consent; 6. Patients with other invasive malignancies within the last 5 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute hematological toxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Other acute and chronic treatment-related toxicity rate;1-year local control rate; | — |
Countries
China
Contacts
Public ContactXie Liangxi
Outcome results
None listed