postoperative pulmonary complications
Conditions
Interventions
Group1: ZEEP:high tidal volume without PEEP
Group2:average optimal PEEP:low tidal volume with average optimal PEEP
Group3: individual PEEP:low tidal volume with individual PEEP
Sponsors
Department of Anesthesiology, West China Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients older than 18 years (and=2 hours; 5. With high or intermediate risk for postoperative pulmonary complications following abdominal surgery; 6. Informed consent obtained.
Exclusion criteria
Exclusion criteria: 1. Mechanical ventilation within the last 30 days before surgery; 2. Body mass index >=30 kg/m2; 3. Severe respiratory disease (pneumonia, history of previous severe chronic obstructive pulmonary disease (COPD), or acute exacerbations of COPD), acute lung injury or acute respiratory distress syndrome; 4. Previous lung surgery; 5. Severe cardiac disease (New York Heart Association class III or IV, or acute coronary syndrome, or persistent ventricular tachyarrhythmias); 6. Shock; 7. Progressive neuromuscular illness; 8. Pregnancy; 9. Participate in other clinical trials within the last 30 days before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pulmonary complications;postoperative extrapulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| hospital stay; | — |
Countries
China
Contacts
Public ContactLiu Bin
Outcome results
None listed