Study on effect andmechanism of compound Huangbai liquid in the treatment of diabetic foot wound

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15007182

Enrollment

Unknown

Registered

2015-10-11

Start date

2015-10-19

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabietic foot

Interventions

compound Huangbai liquid group:compound Huangbai liquid

control group:normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) age over 18 years; 2) patients with diabetic foot ulcers (Texas grade 2-4), the location of ulcer is not limited; 3) diabetic foot infection was mild, moderate, severe (IDSA grade); 4) agree to join the study andsign the informed consent; 5) able to receive regular follow-up after discharge in outpatient andtelephone.

Exclusion criteria

Exclusion criteria: 1) patients with severe lower limb ischemia (ABI 98 mol/L, 106 mol/L); 3) hepatic insufficiency (ALT) 100IU/L; 4) cardiac function 4 (NYHA); 5) patients can not understandthe research program anddo not want to participate.

Design outcomes

Primary

Measure	Time frame
Healing area;Bacterial;Bone tissue pathology;Wound inflammatory factors (IL-6, TNF-alpha);Matrix metalloproteinases andinhibitors in wound;	—

Countries

China

Contacts

Public ContactXu Jun

junxu@tmu.edu.cn+86 13132019724

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026