esophageal cancer
Conditions
Interventions
Group A:elective nodal irradiation (50.4Gy)
Group B:elective nodal irradiation (59.4Gy)
Group C:involved field irradiation (50.4Gy)
Group D:involved field irradiation (59.4Gy)
Sponsors
Shandong cancer hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) the histopathological proofed II - IVa thoracic esophageal squamous cell carcinomas (UICC 2002); 2) ECOG 0-1 level;Life expectancy > 6 months; 3) aged 18 to 70 years old, men or women; can drink the liquid at least; 4) No chemotherapy; 5) No radiotherapy; 6) No surgery; 7) without severe allergies; 8) hemoglobin>100 g/L, the WBC>3.5*10^9/L, neutrophils>1.5*10^9, platele>100*10^9/L; CR<1.5*Upper limit of normal, TB<2.5*Upper limit of normal, AST andALT<2.5*Upper limit of normal, AKP<2.5*Upper limit of normal; 9) barium meal lesion length<10 cm; 10) signed informed consent.
Exclusion criteria
Exclusion criteria: 1) A history of other malignant tumor; 2) repeat esophageal cancer; 3) pregnant or lactating patients; 4) have fertility but did not use contraception; 5) serious complications: extremely high risk of high blood pressure, serious lung function damage, large area of myocardial infarction, cardiac function class II or higher, mental illness or severe diabetes; 6) activity of infectious diseases; 7) participated in other clinical trials 4 weeks prior to the trial; 8) at the same time with other anticancer drug therapy (including anticancer Chinese traditional medicine); 9) after esophageal stent surgery; 10) has a tendency to perforation; 11) has a history of organ transplantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| local-region failure free survival;progression free survival;local-region control rate;treatment toxicity; | — |
Countries
China
Contacts
Public ContactBaosheng Li
Outcome results
None listed