The effect of low-dose intravenous ketamine on cesarean delivery for preventing postpartum depression

The effect of ketamine for preventing postpartum depression: a single-center, randomized, double blind, parallel, superiority clinical trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15007159

Enrollment

Unknown

Registered

2015-09-29

Start date

2015-10-08

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum depression

Interventions

Ketamine group:10ml intravenous injection of ketamine 0.25mg/kg following delivery

Saline group:10ml intravenous injection of 0.9% saline following delivery

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women scheduled for elective cesarean delivery,ASA physical status 1-2 andwhose anesthetic plan is spinal anesthesia are enrolled.

Exclusion criteria

Exclusion criteria: Women are excluded if their body mass index is 40kg/m2 or if they have allergies to any of the study medications, contraindications to spinal anesthesia, or history of psychiatric disease, hallucinations, substance abuse, chronic pain.

Design outcomes

Primary

Measure	Time frame
EPDS(Edinburgh Postnatal Depression Scale) score;	—

Secondary

Measure	Time frame
NRS(Numeric rating scale) score;Cumulative dose of sufentanil;	—

Countries

China

Contacts

Public ContactYuantao Li

sylyt6788@sina.com+86 15013857589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026