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The impact of somatostatin on pancreatic fistula after pancreaticoduodenectomy: A prospective study

The impact of somatostatin on pancreatic fistula after pancreaticoduodenectomy: A prospective study

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007157
Enrollment
Unknown
Registered
2015-09-29
Start date
2015-09-29
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periampullary diseases

Interventions

Somatostatin Group:0.1mg octreotide was used in subcutaneous injection instantly after PD, Q8h, till postoperative day 10
Control Group:same volume of NS was used in subcutaneous injection instantly after PD, Q8h, till postoperative day 10

Sponsors

First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with benign andmalignant periampullary diseases; 2. willing to comply with the study procedures, signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of severe cardiac,pulmonary neural, hepatic andrenal dysfunction; 2. Patient or family refuses to enroll; 3. Based on intraoperative situation, PD cannot be operated; 4. Other.

Design outcomes

Primary

MeasureTime frame
incidence of postoperative pancreatic fistula;

Secondary

MeasureTime frame
incidence of postoperative related complications;incidence of global postoperative complications;intraoperative blood loss;surgical duration;duration of postoperative hospitalization;perioperative mortality;Cost;

Countries

China

Contacts

Public ContactBei Sun
sunbei70@tom.com+86 13603656935

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026