undergoing Colorectal sugery
Conditions
Interventions
Group A(Hydromorphone) :receive PCA-administered Hydromorphone postoperatively
Group B(Sufentanil) :receive PCA-administered Sufentanil postoperatively
Sponsors
First Affiliated Hospital, College of Medicine, Zhejiang University.
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. To be aged between 18-80 years old; 2. Male or female; 3. Body mass index between normal scale+/-20%; 4. ASA I-II; 5. Scheduled for elective,laparoscopic or open surgery for colorectal sugery; 6. Be voluntary to participate the research sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Have a history of mental illness, long-term history of chronic pain take the town for a long time, painkillers, sedatives, anti depression drugs, anti anxiety drug history, NSAIDs drugs, alcohol drug abuse history; 2. Hepatic renal function seriously abnormal; 3. Have a history of abnormal operation or anesthesia; 4. Have a history of gastroesophageal reflux; 5. Those who had received sedatives, antemetic or anticnesmatic within the previous 24 hours; 6. Allergic to opioid; 7. Those who had received MAOI or anti depression drugs within the previous 15 days; 8. Unable to understandVAS score, Digit, Trail Making, unable to use PCA; 9. The patients sended to ICU after operation; 10. Pregnant or lactate; 11. Those who have anxiety or depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median VAS pain scores coughing at rest;PHS score;Mood-POMS evaluate;Cognitive Function Measures; | — |
Secondary
| Measure | Time frame |
|---|---|
| satisfaction;anal exsufflation time;post-operative hospital stay;the time to wal; | — |
Countries
China
Contacts
Public ContactZhiying Feng
Outcome results
None listed