opioid-induced constipation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients recieve analgesic therapy with daily uge of oxycodone hydrochloride delayed release tablets >=80 mg; 2. those who meet the diagnostic criteria of rome ? for constipation; 3. those aged between 18 80 years old; 4. those no other management for constipation during 2 weeks before enrollment except rescue symptomatic treatment for acute intestinal obstruction gas; 5. those who have no language barrier signed informed consents.
Exclusion criteria
Exclusion criteria: 1. patients with other secondary constipation caused by metabolic, endocrine, nervous, postoperative diseases or intestinal organic diseases (such as crohns disease, intestinal tuberculosis, etc.); 2. those who accompanied by serious cardiovascular, hepatic, renal, or psychiatric diseases, influencing the cooperation, examination or follow-up process of taifc; 3. pregnant or lactating women.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| numeric rating scales;patient assessment of constipation quality of life; | — |
Primary
| Measure | Time frame |
|---|---|
| cleavelconstipation scales; | — |
Countries
China