gynecologic laparoscopic surgery
Conditions
Interventions
Two groups:dexmedetomidine versus control
Sponsors
Peking University, First Hospital
Eligibility
Sex/Gender
Female
Age
23 Years to 60 Years
Inclusion criteria
Inclusion criteria: ASA physical status I or II patients, between 18 and 65 yr old, undergoing elective laparoscopic gynecological surgery were enrolled for removal of ovarian tumors and cysts, myomectomy, and laparoscopic assisted vaginal hysterectomy.
Exclusion criteria
Exclusion criteria: Exclusion criteria included age65 years, a history of uncontrolled hypertension, heart block greater than first degree, obesity (body mass index >30 kg/m2), pregnancy, breast-feeding, known hypersensitivity to drugs used in the study protocol, use of antiemetics, psychotropic drugs and steroids within 24h before surgery. Patients with known comorbidities that could increase the incidence of PONV were also excluded, such as diseases which impaired gastric motility (gastric and intestinal disease, neuromuscular disorders, neuropathies, and liver dysfunction), vestibular disease, central nervous system injury, renal impairment, alcoholism, and opioid addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of 24h PONV; | — |
Countries
China
Contacts
Public ContactWang Dongxin
Outcome results
None listed