Infertility, poor ovarian response
Conditions
Interventions
DHEA group:DHEA 3 tablets daily for 12 weeks
Placebo group:Placebo 3 tablets daily for 12 weeks
Sponsors
Center for Reproductive Medicine, Shandong University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. women who had tried to become pregnant for at least 1 year; 2. women with regular menses defined as the length of cycle 21~35 days; 3. women diagnosed with poor ovarian response according to Bologna consensus.
Exclusion criteria
Exclusion criteria: 1. women who had failed in 3 or more IVF cycle with ovarian stimulation and oocyte pickup; 2. women diagnosed with uterine malformation or abnormality; 3. women diagnosed with hydrosalpinx in hysterosalpingography; 4. women who had a history of spontaneous miscarriage for 2 times or more (biochemical miscarriage does not count in); 5. couples with female or male abnormal karyotype; 6. women who had undergone chemotherapy with cytotoxic agents; 7. women who had undergone pelvic radiotherapy; 8. women who had taken DHEA before enrollment; 9. women with a history of epilepsy; 10. women who is allergic to DHEA; 11. women who is using insulin; 12. women with contraindications to assisted reproductive technology or pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live biirth rate; | — |
Countries
China
Contacts
Public ContactZi-Jiang Chen
Outcome results
None listed