Aerophagia
Conditions
Interventions
Group A:Itopride Hydrochloride Tablets
Group C:Itopride Hydrochloride Tablets + Flupentixol and Melitracen Tablets
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 76 Years
Inclusion criteria
Inclusion criteria: The patients with clinical symptoms accords with diagnostic criteria Rome III: all the following qualifications must be included: 1. Recurrent belching at least several times a week; 2. Air swallowing can be observed or detected objectively. Those symptoms are existed at least 6 months before diagnosis, and met the criterion for almost three months.
Exclusion criteria
Exclusion criteria: 1. Patients with severe psychical and psychological diseases (serious depression, anxiety, personality disorder or suicide inclination: if visual or auditory hallucination appeals, it's better to transferred to psychiatric departments); 2. Patients with (critical) organic lesion in gastrointestinal, liver, gallbladder, pancreas, heart, kidney,etc. Patients with infectious, hereditary, metabolic, endocrine, autoimmune diseases etc.; 3. Patients with allergic history, alcohol or drug abuse history; 4. Patients with badly heart diseases, like early recovery of acute myocardial infarction(AMI), bundle branch block; Patients with untreated narrow cleft glaucoma; Patients with highly excitation; Patients with acute alcohol, barbiturates, opium intoxication; Patients during pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom score of Aerophagia (ten-point calibration);Safety Evaluation (TESS side effect rating scale); | — |
Countries
China
Contacts
Public ContactSenlin Zhu
Outcome results
None listed