Recurrent Respiratory Tract Infections in Children
Conditions
Interventions
Experimental Group:Yu Ping Feng Granule
Active Control Group:Pidotimod Oral Solution
Placebo Group:Placebo
Sponsors
Beijing Children Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Subjects are diagnosed as pediatric recurrent respiratory tract infections; 2. Subjects are not in acute infection or recovered from acute infection no less than 1 week; 3. The symptoms of subjects are in accordance to the traditional Chinese medicine syndrome category; 4. Age between 2 to 6; 5. Informed consent forms must be signed by parents or legal guardians of the subjects.
Exclusion criteria
Exclusion criteria: 1. Patients with respiratory infection caused by primary immunodeficiency disease, congenital pulmonary airway malformation, gastroesophageal reflux disease (GERD), and pulmonary dysplasia; 2. Used immunosuppressants or immunoenhancive drug within 1 month, or use other treatments for RRTI; 3. Patients with severe malnutrition, rickets, anemia, asthma, and/or other vital organ disease, including those ALT level exceed 1.5 times than normal upper limit, or Cr level exceed normal upper limit; 4. Patients who are allergic to the experimental drug or allergic to more than one food or drugs; 5. Subjects who Deemed to be not appropriate to attend the trial or having problem completing the trial; 6. Subjects who attended other clinical trials within 3 monthes.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| reduce the ratio of recurrent infections;Effects on TCM Symptoms;Effects on Single Symptom;Complete Blood Count;Blood Chemistry Tests; | — |
Primary
| Measure | Time frame |
|---|---|
| RRTI Cure rate; | — |
Countries
China
Contacts
Public ContactShen Kunling
Beijing Children Hospital, Capital Medical University
Outcome results
None listed