gastrointestinal tumors
Conditions
Interventions
Group 1:oxycodone hydrochloride 0.01mg/kg/bolus
Group 2:oxycodone hydrochloride 0.02mg/kg/bolus
Group 3:oxycodone hydrochloride 0.03mg/kg/bolus
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. ASA class I-III; 2. Chinese male or female subjects aged >= 65 and <= 90 years; 3. They are planned to undergo laparoscopic gastrointestinal tumor resection; 4. The subjects can communicate well with the researchers and can complete the research in accordance with the research regulations.
Exclusion criteria
Exclusion criteria: 1. Subjects who endured severe pain for a long time before participating in the trial; 2. Subjects who took other analgesic drugs for a long time before participating in the trial; 3. Subjects with poor preoperative basic conditions and multiple diseases, including severe liver and kidney dysfunction, severe cardiovascular and cerebrovascular diseases or mental diseases; 4. Hypersensitivity to oxycodone and its antagonists.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score of the rest and active pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| the total and effective number of press in PCIA;cumulative dose of oxycodone used in PCIA;nausea;vomiting;dizziness;patients’ satisfaction; | — |
Countries
China
Contacts
Public ContactLiao Qin
Outcome results
None listed