Clinical efficacy and anti-inflammatory effects loading dose of atorvastatin before elective PCI in STEMI

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006785

Enrollment

Unknown

Registered

2015-03-23

Start date

2013-08-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST-segment elevation acute myocardial infarction

Interventions

Experimental group:loading 2-day statin therapy before operation

Control group:Regular dose statin therapy

Eligibility

Sex/Gender

All

Age

20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age of 20-75 years old; 2. Clear time of onset and admissions within 48 hours after onset who were confirmed STEMI; 3. STEMI undergoing primary PCI or thrombolysis failed; 4. First success in CAG + PCI after admission

Exclusion criteria

Exclusion criteria: 1. Killip>=grade III; LVEF=1; 8. Myopathy or higher CK greater than 2 times the upper limit of the normal reference value; 9. Renal insufficiency, Creatinine >=2mg/dl; 10. WBC<=4*10^9/L, PLT<=50*10^9/L; 11. Life expectancy is less than 2 years with non-cardiovascular diseases; 12. Pregnant and lactating women; 13. Involved in other clinical studies; 14. Other situations which the researchers believe that it is not suitable for studies.

Design outcomes

Primary

Measure	Time frame
Cytokines;	—

Countries

China

Contacts

Public ContactChengwei Liu

whlcw60@126.com+86 18963980513

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026