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A randomized controlled clinical trial of Tanreqing Injection in patients with dengue fever.

Efficacy and safety of Tanreqing injection in patients with dengue fever: a randomised, proof-of-concept trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15006778
Enrollment
Unknown
Registered
2015-07-21
Start date
2015-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dengue

Interventions

control group:Symptomatic treatment

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients had met at least two criteria indicating probable dengue infection (on the basis of the 2014 National Health and Family Planning Commission of PRC dengue classifi cation scheme),and had a positive result on a dengue NS1 antigen or PCR assay. (2) Patients aged 18–65 years; (3) Patients had a fever (>38 degree C) for less than 48 h; (4) Patients agreed to participate in this research and sign the informed consent file.

Exclusion criteria

Exclusion criteria: (1) Patients with severe bleeding, including subcutaneous hematoma, hematemesis, melena, vaginal bleeding, hematuria, intracranial hemorrhage,etc; (2) Patients with dengue shock complication, Appeared heartbeat speed, acromegaly wet, capillary filling time prolonged > 3 seconds, pulse slim and fragile or undetectable, pulse pressure or the decrease of the blood pressure measurement,etc; (3) Patients with severe organ damage occurred: for wexample,liver damage (ALT and / or AST > 1000 IU/L), ARDS, acute myocarditis, acute renal failure, encephalopathy and encephalitis; (4) pregnant or nursing; (5) Patients with a history of allergies and Tanreqing allergy; (6) Patients who participated in the other clinical trials in the last 1 months.

Design outcomes

Primary

MeasureTime frame
Duration of fever;Wihte blood cell count;

Secondary

MeasureTime frame
the rate of main symptoms disappeared;Platelet count;

Countries

China

Contacts

Public ContactLi jun
13728065350@163.com+86 13728065350

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026