Effect of dexmedetomidine on perioperative sedation and analgesia and intrapulmonary shunt in patients undergoing Lobectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006727

Enrollment

Unknown

Registered

2015-07-10

Start date

2015-07-20

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sedation and analgesia and intrapulmonary shunt

Interventions

C group:No

DV group:Intravenous dexmedetomidine

DE group :epidural infusion of dexmedetomidine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients undergoing Lobectomy

Exclusion criteria

Exclusion criteria: Age>=65;a history of heart disease, neural disease and diabetes; chronic hepatic or renal insufficiency;coagulopathy; a history of alcohol or analgesics dependence; chronic pain; a history of relevant drug allergy; refuse to undergoing epidural anaesthesia.

Design outcomes

Primary

Measure	Time frame
vital signs;BIS;oxygenation index;pulmonary dynamic compliance;intrapulmonary shunt fraction;arterial blood gas analysis;postoperative analgesia and sedation score;intraoperative propofol consumption;postoperative sufentanil consumption;blood dexmedetomidine concentration in DV and DE group;inoperative awareness;	—

Countries

China

Contacts

Public ContactWengang Ding

dingwg999@163.com+86 13936563265

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026