Vaginal delivery
Conditions
Interventions
control group:levobupivacaine
experiment group:dexemetomidine
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Gestational age >=37 weeks; with an engaged vertex presentation; intact membrane; active labor with cervical dilatation >3 cm and uterine contractions occurring at least every 5 min; normal cardiotocography (CTG) [baseline fetal heart rate (FHR) between 110 and 160 beats/minute, baseline variability >5 beats/minute, presence of accelerations, and absence of decelerations].
Exclusion criteria
Exclusion criteria: Subjects were excluded if they had pregnancy-induced hypertension (PIH) (preeclampsia), concomitant cardiovascular disease, documented coagulation abnormality or abnormal bleeding history, evidence of infection or anatomic abnormality at the proposed catheter insertion site, if they declined study participation or were unable to give informed voluntary consent, or were younger than 18 years. Subjects were also excluded from the study in cases of difficult epidural placement, inadvertent epidural puncture (wet tap), rapid progress of labor (delivery in less than 120 minutes of study period), or fetal distress mandating urgent/emergent cesarean delivery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;number of PCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation score; | — |
Countries
China
Contacts
Public ContactChen XI
Outcome results
None listed