Preoperative short-course radiotherapy with local boost versus conventional preoperative short-course radiotherapy for local advanced rectal cancer: phase II clinical trail

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006683

Enrollment

Unknown

Registered

2015-06-30

Start date

2015-07-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

study group:preoperative short-course radiotherapy with local boost

control group:preoperative short-course radiotherapy without local boost

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Local advanced rectal cancer (TNM Stage: T3-4NxM0 )diagnosed by biopsy and MRI or Endoscopic ultrasonography; 2. Distance between tumour and anal edge =70; 4. Liver and kidney functions are normal; 5. Without any anticancer treatment before inclusion.

Exclusion criteria

Exclusion criteria: 1. Metastasis; 2. Combined with other severe diseases, such as other kind of cancer, COPD, Miocardial infarction, ect.; 3. Included in other clinical trails.

Design outcomes

Primary

Measure	Time frame
Pathological complete remission rate;	—

Secondary

Measure	Time frame
Sphincter preservation rate;toxicity of radiotherapy;	—

Countries

China

Contacts

Public ContactZhou Fuxiang

happyzhoufx@sina.com+86 18971252780

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026