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Study of preventing and controlling of delirium in ventilated patients by simulating the circadian clock sedation in ICU

Study of preventing and controlling of delirium in ventilated patients by simulating the circadian clock sedation in ICU

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15006644
Enrollment
Unknown
Registered
2015-06-23
Start date
2015-06-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

delirium

Interventions

the simulating the circadian clock group:analgesia treatment and sedative drugs (simulating the circadian clock)
the control group:analgesia treatment and sedative drugs (non-simulating the circadian clock)

Sponsors

The Second Hospital of Lanzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with mechanical ventilation treatment of 12 h or more in ICU; 2. Ages 18 to 65 years,Sex unlimited.

Exclusion criteria

Exclusion criteria: 1. Coma, dementia patients, patients with craniocerebral injury and after cardiac surgery; 2. A history of alcoholism or drug dependence and severe complication of patients,severe liver failure, kidney failure; 3. Left ventricular ejection fraction < 0.30, II, III atrioventricular block, acute myocardial infarction, severe bradycardia, malignant arrhythmia; 4. Pregnancy and nursing mothers.

Design outcomes

Primary

MeasureTime frame
mechanical ventilation time;extubation time;ICU length of stay;the incidence of delirium rate;6-hydroxy acid melatonin;

Countries

China

Contacts

Public ContactDong Chenming
dongcm0608@163.com+86 13893231628

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026