delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with mechanical ventilation treatment of 12 h or more in ICU; 2. Ages 18 to 65 years,Sex unlimited.
Exclusion criteria
Exclusion criteria: 1. Coma, dementia patients, patients with craniocerebral injury and after cardiac surgery; 2. A history of alcoholism or drug dependence and severe complication of patients,severe liver failure, kidney failure; 3. Left ventricular ejection fraction < 0.30, II, III atrioventricular block, acute myocardial infarction, severe bradycardia, malignant arrhythmia; 4. Pregnancy and nursing mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mechanical ventilation time;extubation time;ICU length of stay;the incidence of delirium rate;6-hydroxy acid melatonin; | — |
Countries
China