sedation after cardiac surgery
Conditions
Interventions
Control group:Propofol
Sponsors
The First Affiliated Hospital, School of Medicine Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 150 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old; 2. Selective cardiac surgery; 3. Used caridopulomonary bypass during operation; 4. Transferred into intensive care unit and need for invasive mechanical ventilation
Exclusion criteria
Exclusion criteria: 1. Acute severe neurological disorder; 2. Mean arterial pressure less than 55mmHg despite appropriate intravenous volume replacement and vasopressors; 3. Heart rate less than 50/min; 4. Atrioventricular-conduction grade II or III (unless pacemaker installed); 5. Of dexmedetomidine or propofol allergy or other contradications; 6. Diabetes patients with insulin dependent; 7. Body mass index(BMI)>= 30kg/m^2; 8. Second or more operations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sublingual microcirculation;SOFA score;APACHEII score;Complicaitoins after sedation during ICU stay;Serum lactate level;Length of ICU stay;Postoperative length of hospital stay; | — |
Countries
China
Contacts
Public ContactFang Xiangming
The First Affiliated Hospital School of Medicine Zhejiang University
Outcome results
None listed