lung cancer
Conditions
Interventions
1:Patients will receive saline during and after operation.
2:Patients will receive 0.3ug?kg-1?h-1 dexmedetomidine until skin suture after 0.5ug?kg-1 bolus with 15 minutes before anesthesia induction.
3:Add dexmedetomidine 200 ug into postoperative venous analgetic pump.
4:1.Patients will receive 0.3ug?kg-1?h-1 dexmedetomidine until skin suture after 0.5ug?kg-1 bolus with 15 minutes before anesthesia induction. 2.Add dexmedetomidine 200 ug into postoperative venous an
Sponsors
Shenzhen People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 70; 2. patients with lung cancer; 3. ASA I-II stage; 4. Estimated blood loss less than 10% of total blood volume.
Exclusion criteria
Exclusion criteria: 1. Patients with systemic metastasis; 2. Patients received preoperative radiotherapy; 3. Patients with preoperative chemotherapy; 4. Patients received statins in one month; 5. Severe cardiac tachycardia; 6. Severe cardiac block; 7. Hypertension; 8. Coronary heart disease; 9. Diabetes; 10. Hyperthyrea; 11. Coagulation disorders; 12. Patients with mental disorders who can not complete visual analog scale; 13. Patients received sedative and analgesic drugs in 48 hours; 14. Patients with drug allergies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| extubation time;blood pressure;heart rate;immune index;circulating tumor cell;stress response index;postoperative analgesic effect;the anesthetic dosage;length and expenses of hospital stay;adverse event; | — |
Countries
China
Contacts
Public ContactDengfeng Ding
Outcome results
None listed