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The research on the pharmacodynamic and pharmacokinetic of low-dose ticagrelor in healthy Chinese population

The research on the pharmacodynamic and pharmacokinetic of low-dose ticagrelor in healthy Chinese population

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15006505
Enrollment
Unknown
Registered
2015-06-04
Start date
2015-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cornary Heart Disease

Interventions

standard dose of ticagrelor:90mg bid
low dose of ticagrelor:45mg bid
standard dose of clopidogrel:75mg qd

Sponsors

Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy adult age 18-45 years old; Voluntary clinical trials, And signed informed consent.

Exclusion criteria

Exclusion criteria: 1. contraindication to antiplatelet therapy; 2. haemoglobin 2 times the upper normal limit; 6. chronic renal failure (creatinine clearance<30 mL/min); and 7. active peptic ulceration or gastrointestinal bleeding.

Design outcomes

Primary

MeasureTime frame
PRU;

Countries

China

Contacts

Public ContactLiping Ma
mlp-125@163.com+86 15921008819

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026