Neuroprotective effect of dexmedetomidine in patients undergoing meningioma resection

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006498

Enrollment

Unknown

Registered

2015-05-13

Start date

2015-05-20

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningiomas

Interventions

1:using dexmedetomidine for anesthesia

2:without dexmedetomidine for anesthesia

Eligibility

Sex/Gender

All

Age

45 Years to 65 Years

Inclusion criteria

Inclusion criteria: 40 ASA physical status II-III patients, who are scheduled for meningioma resection, with the age from 45-65 years old and BMI from 20-30, operation time will be 2-4h

Exclusion criteria

Exclusion criteria: 1. Patients with a history of alcohol abuse or antipsychotic use; 2. severe cardiac, pulmonary, hepatic, or renal disease; 3. Pregnant or lactating women; 4. HR<60bpm or SBP<100mmHg

Design outcomes

Primary

Measure	Time frame
NSE;S100beta protein;BDNF;GFAP;HR;BP;	—

Secondary

Measure	Time frame
MMSE(Mini-Mental State Examination);	—

Countries

China

Contacts

Public ContactWang SL

wshlei@aliyun.com+86 18661806773

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026