Effects of NSAIDs on the postoperative outcome of cancer patients with thoracotomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006482

Enrollment

Unknown

Registered

2015-06-01

Start date

2015-06-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer patients with thoracotomy

Interventions

control:placebo

intervention:NSAIDs

Eligibility

Sex/Gender

All

Age

60 Years to 75 Years

Inclusion criteria

Inclusion criteria: 160 patients undergoing esophageal resection with an ASA status I-II, male or female, 60-75 years old. Preoperative normal pulmonary function,and no received radiotherapy, chemotherapy and immunosuppressive agents. The same type of surgery is operated by the same group of doctors, and written informed consent was obtained from all enrolled patients.

Exclusion criteria

Exclusion criteria: 1. severe liver and kidney dysfunction, coagulation abnormalities and perioperative allogeneic blood; 2. autoimmune disease or immunocompromised patients; 3. cardiovascular adverse reactions,gastrointestinal bleeding in patients after using NSAIDs; 4. high blood pressure, severe heart failure; 5. enoxacin, lomefloxacin, norfloxacin being used; 6. others is unsuitable for selected.

Design outcomes

Primary

Measure	Time frame
Blood gas analysis;Immunoglobulin;Survival rate;	—

Countries

China

Contacts

Public Contactchai xiaoqing

xiaoqingchai@163.com+86 551-62283912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026