Helicobacter pylori infection
Conditions
Interventions
Amoxicillin-containing quadruple therapy :Amoxicillin-containing quadruple therapy
Cefuroxime-containing quadruple therapy:Cefuroxime-containing quadruple therapy
Sponsors
Department of Gastroenterology, Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Consecutive patients with dyspepsia who are referred to our hospital for upper endoscopy; 2. HP RUT and W-S staining positive; 3. Penicillin skin test negative; 4. Never received treatment for H. pylori infection; 5. Aged 20 to 70 years; 6. Willing and available for participation this study.
Exclusion criteria
Exclusion criteria: 1. Taking any drug which could influence the study results such as PPI, H2-receptor blockers, bismuth salts and antibiotics in the previous 4 weeks; 2. Gastrointestinal malignancy; 3. Zollinger-Ellison syndrome; 4. Previous gastric and esophageal surgeries 5. Severe concomitant cardiovascular, respiratory, renal, hepatic, hematological, neurological, endocrine or psychiatric diseases; 6. History of allergy to any of the drugs used in the study; 7. Pregnancy or lactation; 8. Any other clinically significant medical condition that could increase risk of side effects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event rate;Compliance; | — |
Countries
China
Contacts
Public ContactLiya ZHOU
Outcome results
None listed