Skip to content

The effect of intraoperative dexmedetomidine on renal function after endovascular aneurysm repair operation in stanford type B aortic dissection patients: a randomized, double-blind, controlled trial

The effect of intraoperative dexmedetomidine on renal function after endovascular aneurysm repair operation in stanford type B aortic dissection patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15006372
Enrollment
Unknown
Registered
2015-05-10
Start date
2016-12-01
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stanford type B aortic dissection

Interventions

dexmedetomidine:Intraoperative dexmedetomidine pump
Control:Intraoperative saline pump

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
29 Years to 83 Years

Inclusion criteria

Inclusion criteria: The study included patients(aged >= 18 years), with American Society of Anesthesiologists (ASA) physical status II-III, who were diagnosed as stanford type B aortic dissection and scheduled to undergo selective endovascular aneurysm repair(EVAR) procedure.

Exclusion criteria

Exclusion criteria: sick sinus syndrome, severe bradycardia (heart rate [HR] < 50 beats/min), left ventricular ejection fraction < 30% or heart failure, atrioventricular block, history of allergy to dexmedetomidine, lesion affecting the accessory renal artery or decline to sign the informed consent. Those patients in which surgical approach (EVAR) were switched to other surgical procedures such as vascular replacement surgery, were also excluded from the study.

Design outcomes

Primary

MeasureTime frame
acute kidney injury;

Secondary

MeasureTime frame
serum creatinine;estimated glomerular filtration rate;serum cystatin C;urine output;any postoperative complication;postoperative stroke;postoperative pneumonia;postoperative deep venous thrombosis;postoperative mesenteric venous thrombosis;postoperative cognitive dysfunction;length of ICU stay;length of hospital stay;

Countries

China

Contacts

Public ContactFuHai Ji

The First Affiliated Hospital of Soochow University

jifuhai@hotmail.com+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 21, 2026