chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
A:positive end-pxpiratory pressure device and combivent
B:positive end-pxpiratory pressure device and saline
C:ultrasonic nebulization and combivent
D:oxgyen nebulization and combivent
Sponsors
The first affiliated hospital of guangzhou medical university
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. April, 2015 -January, 2016 was diagnosed as COPD patients,and hospitalized in the First Affiliated Hospital of Guangzhou medical university; 2. met the diagnostic criteria of chronic obstructive pulmonary disease (pulmonary function test): FEV1/FVC<70%; 3. subjects cooperate with pulmonary function tests, induced sputum test, 6 min walking distance; 4. subjects participated in the study, and informed consent.
Exclusion criteria
Exclusion criteria: 1. there are other lung except COPD disease (such as bronchiectasis, bronchial asthma, pneumonia, pulmonary embolism, pneumothorax); 2. they could not complete pulmonary function test, sputum induction test, 6min walking distance check; 3. heart disease serious arrhythmia, chronic heart failure or myocardial ischemia; 4. with organ dysfunction and malignant tumor; 5. severe respiratory failure, ventilator support; 6. the use of combivent contraindicated in patients with hypertrophic obstructive cardiomyopathy: 1, the rapid arrhythmia of patients, combivent any allergy ingredients and its derivatives. The pregnant and nursing women. Patients with hypokalemia. 7. do not have legal capacity or limited legal capacity; 8. does not agree to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total sputum of 24h;the color of sputum;WBC, N, PCT, CRP, ESR;6MWD;The total weight of 24h sputum;CAT; | — |
Countries
China
Contacts
Public ContactZheng Zeguang
Outcome results
None listed