cerebral palsy
Conditions
Interventions
The experimental group 9 to 18 months:3U/Kg botulinum toxin A injection and Rehabilitation training
The experimental group 9 to 18 months:5U/Kg botulinum toxin A injection and Rehabilitation training
The experimental group 18 to 36 months:3U/Kg botulinum toxin A injection and Rehabilitation training
The experimental group 18 to 36 months:5U/Kg botulinum toxin A injection and Rehabilitation training
The control group 9 to 18 months:Rehabilitation training
The control group 18 to 36 months:Rehabilitation training
Sponsors
The third affiliated hospital of Zhengzhou university
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: 1. meet to the diagnosis standard of spasm cerebral palsy; 2. the spasm of cerebral palsy children with tetraplegia, double paralysis, hemiplegia from 2015.05 to 2017.01 at Rehabilitation Center for Children with Cerebral Palsy in Henan Province, the Third Affiliated Hospital of Zhengzhou University; 3. In the lower extremities calf, hamstring and adduction muscle group for the target muscle; 4. the age between 9 and 36 months old.
Exclusion criteria
Exclusion criteria: 1. Allergic constitution, severe liver and kidney function damage; 2. Neuromuscular joint lesions; The injection site andother areas of the body is infection; 3. Drugs which can increase nerve muscle joint disorder in 1week was applied; 4. Existing joint fixed, severe muscle contracture injection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Tardieu scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gross Motor Function Measure;Passive Rang Of Motion;pennation angle;fascicle lengths;thickness of muscle; | — |
Countries
China
Contacts
Public ContactZhu Dengna
The Third Affiliated Hospital of Zhengzhou University
Outcome results
None listed