diabetes
Conditions
Interventions
1:exenatide group
2:Diet+movement
Sponsors
The first afilliated hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: The patients who have finished study A (Effect of Short-Term Intensive Insulin Sequential Exenatide Therapy on beta-cell Function and Glycemic Remission Rate in Newly Diagnosed Type 2 Diabetic Patients This study was registered with ClinicalTrials.gov, number number NCT01776788) will be enrolled. Inclusion criteria of study A: Newly diagnosed Type 2 Diabetic Chinese Patients; To be aged from 30 to 70 years; FPG 7.0-16.7mmol/L; BMI 20-35 kg/m2, stable body weight (<10% variation) for at least 3 months prior to screening female patients of reproductive age should practice a reliable method of birth control throughout the study.
Exclusion criteria
Exclusion criteria: Exclusion Criteria of study A 1. acute or severe chronic diabetic complications; 2. Recently suffered from MI or CVA; 3. severe gastrointestinal disease; 4. other severe intercurrent illness. 5. serum aminotransferase (ALT and AST) level higher than 2 times of the upper normal limits and/or serum creatinie >133umol/L (1.5mg/dL); 6. tested positive for glutamic acid decarboxylase antibody; 7. use of weight loss drugs, corticosteroids, drugs known to affect gastrointestinal motility, transplantation medications, or any investigational drug; 8. history of pancreatitis; 9. Pregnant or lactation women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| remission rate; | — |
Countries
China
Contacts
Public ContactXuejun Li
Outcome results
None listed