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Randomized controlled trial of genotype matched blood transfusion in patients with autoimmune hemolytic anemia

Randomized controlled trial of genotype matched blood transfusion in patients with autoimmune hemolytic anemia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15006275
Enrollment
Unknown
Registered
2015-01-19
Start date
2015-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autoimmune hemolytic anemia,AIHA

Interventions

The type of traditional blood transfusion:Minimum compatible with type a blood transfusion
The type of genotype matched blood transfusion:genotype matched blood transfusion

Sponsors

Department of Blood Transfusion, The Second Affiliated Hospital, Third Military Medical University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Hemolytic crisis patients: the anemia progress rapidly and serious, life-threatening; 2. Serious autoimmune hemolytic anemia: Hb<40g/L or Hct<0.13, but the hemolysis is stable and not life-threatening; 3. AIHA patients with chronic hemolysis: patients with signifiant signs and symptoms, such as lethargy, unresponsive, mental confusion or coma and other central nervous system symptoms, and hormone therapy does not work(Hb <50g/L, reticulocytes <10 %).

Exclusion criteria

Exclusion criteria: 1. Hb >60g/L; patients without hemolytic crisis; 2. Patients woth gastrointestinal bleeding or other bleeding disorders.

Design outcomes

Primary

MeasureTime frame
Hemoglobin;Autoantibody;iso-antibody;—

Secondary

MeasureTime frame
Direct anti human globulin;Indirect anti human globulin;—

Countries

China

Contacts

Public ContactLi Zhongjun
johnusc@gmail.com+86 13500373622

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026