acute gout arthritis
Conditions
Interventions
prednisolone group :prednisolone 35mg qd
etoricoxib group :etoricoxib 120mg qd
Indomethacin group :Indomethacin 50mg tid
Sponsors
Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: The patients were >=18 years with acute gout within 72 hours of onset and were diagnosed according to the 1977 American College of Rheumatology classification criteria and at least moderate pain intensity (2 on a 5-point Likert scale) in the target joint at baseline.
Exclusion criteria
Exclusion criteria: Patients were excluded if there was a clinical suspicion of sepsis or other joint disease; polyarticular gout involving more than four joints; allergic reactions to any component of the study drugs, if follow-up was impossible because of lack of transport or lack of telephone contact; and if patients had dementia, confusion, active gastrointestinal symptoms, renal insuf?ciency with serum creatinine level greater than 200 umol/L, bleeding disorder, or were taking warfarin. Pregnant or breastfeeding women were excluded. We did not allow non-steroidal anti-inflammatory drugs or prednisolone within 72 hours before baseline assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| joint pain intensity; | — |
Secondary
| Measure | Time frame |
|---|---|
| joint tenderness;joint erythema;joint swelling; | — |
Countries
China
Contacts
Public ContactLingling Xu
Outcome results
None listed