The comparison between Hydroxyethyl Starch(HES) 6% 130/0.4 in a Balanced Electrolyte Solution (Volulyte) and 6% HES130/0.4 saline (Voluven) During Cardiac Surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006241

Enrollment

Unknown

Registered

2015-04-13

Start date

2015-05-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatic heart valve disease

Interventions

A:Voluven

B:Volulyte

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>18 years; 2. ASA I-III; 3. An expected time of cardiopulmonary bypass between 1 to 3 hours; 4. Local is less than 2500 meters above sea level.

Exclusion criteria

Exclusion criteria: 1. A<=18years 2. A history of cardiac surgery; 3. Hemoglobin concentration 10 g/dL and 17 g/dL before study admission; 4. Take anticoagulants before 5 days; 5. coagulation disorders; 6. Can't evaluate the blood loss perioperative and postoperative; 7. Hepatic and Renal disfunction; 8. Electrolyte disorder; 9. Preoperative inflammatory disease is not cured; 10. Albumin in CPB; 11. acetate allergies; Hydroxyethyl starch allergies; 12. Within 3 month before the 12 selected research take other test drugs or engage in other clinical trials; 13. Family members refused to participate.

Design outcomes

Primary

Measure	Time frame
Blood coagulation function;liver, kidney functions;	—

Countries

China

Contacts

Public ContactWang Haiying

2371827590@qq.com+86 13885218901

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026