Hypotension
Conditions
Interventions
Two groups:Phenylephrine, norepinephrine, I.V. 0-6 mcg Approximately 60 min versus Phenylephrine, norepinephrine 0-100 mcg Approximately 60 min
Sponsors
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients scheduled for elective or non-elective caesarean delivery under spinal anaesthesia during normal working hours at Prince of Wales Hospital, Shatin, Hong Kong. In keeping with the pragmatic study design, inclusion criteria will be broad and all patients having caesarean delivery will be assessed for suitability except for those matching the specific exclusion criteria.
Exclusion criteria
Exclusion criteria: Known fetal abnormality, inability or refusal to give informed consent, age < 18 years, patients taking monoamine oxidase inhibitors or tricyclic antidepressants, patients with mesenteric or peripheral vascular thrombosis, patients with renal impairment, known allergy to phenylephrine or norepinephrine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Umbilical arterial blood pH; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of maternal hypotension.;Incidence of maternal bradycardia.;Incidence of maternal nausea or vomiting.;Other umbilical arterial and venous blood gas parameters.; | — |
Countries
China
Contacts
Public ContactProfessor Warwick Dean Ngan Kee
The Chinese University of Hong Kong
Outcome results
None listed