postprandial hypotension
Conditions
Interventions
diabetic patients with poatprandial hypotension:acarbose100mg
Placebo:placebo
DM patients without low blood pressure:N/A
Sponsors
Beijing Hospital of Ministry of Public Health
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: All patients were diagnosed with type 2 diabetes according to 1999 World Health Organization (WHO) criteria, aged between 60 and 80 years, and were receiving insulin treatment but not receiving oral anti-diabetic drugs treatment. Glycohemoglobin (HbA1c) values were between 7% and 11%.Postprandial hypotension (PPH) was defined as a decrease in systolic blood pressure of >=20 mm Hg or a decrease below 90 mm Hg from a pressure of >=100 mm Hg within 2 hours after a meal.
Exclusion criteria
Exclusion criteria: Exclusion criteria were: a history of renal disease with a plasma creatinine concentration of 133 umol/L (1.5 mg/dL) or more; severe gastrointestinal diseases; severe cardiac diseases (a history of unstable angina or myocardial infarction within the previous 6 months or New York Heart Association class III or IV congestive heart failure); hepatic diseases, or an aspartate aminotransferase or alanine aminotransferase concentration at least twice as high as the upper limit of the normal range; endocrine diseases (hypothyroidism, hyperthyroidism, Cushing's syndrome); uncontrolled hypertension (systolic blood pressure >=160mmHg or diastolic blood pressure >=95mmHg) or using drugs that can affect the blood pressure or heart rate such as cardio-active drugs or antihypertensive drugs (e.g., digitalis, diuretics, anti-angina agents, ACEI/ARB, beta-blockers, or CCB).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postprandial hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate variability; | — |
Countries
China
Contacts
Public ContactLixin Guo
Outcome results
None listed