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Targeted percutaneous microwave ablation at the pulmonary lesion combined with mediastinal radiotherapy with or without concurrent chemotherapy in locally advanced non-small-cell lung cancer evaluation in a prospective randomized controlled study

Targeted percutaneous microwave ablation at the pulmonary lesion combined with mediastinal radiotherapy with or without concurrent chemotherapy in locally advanced non-small-cell lung cancer evaluation in a prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15006087
Enrollment
Unknown
Registered
2015-03-12
Start date
2015-03-12
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

locally advancednon-small-cell lung cancer

Interventions

percutaneous microwave ablation at pulmonary lesio :percutaneous microwave ablation at pulmonary lesion combined with mediastinal radiotherapy or chemoradiotherapy
Control:mediastinal radiotherapy or chemoradiotherapy

Sponsors

Pingyi branch of Qilu Hospital; Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Karnofsky performance scale (KPS) score >60 points; 2. pulmonary reserve greater than severe obstructive or severe restrictive ventilatory dysfunction; 3. histopathology confirmed the stage IIIA or IIIB NSCLC.

Exclusion criteria

Exclusion criteria: 1. KPS score <=60 points; 2. pulmonary reserve was severe obstructive or severe restrictive ventilatory dysfunction; 3. severe liver and kidney dysfunction; 4. severe coagulopathy.

Design outcomes

Primary

MeasureTime frame
radiation pneumonia;1 year OS;—

Contacts

Public ContactXinglu Xu
xlk2002@126.com+86 15589006620

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026