uremia
Conditions
Interventions
low calcium concentration dialysate :low calcium concentration dialysate
physiological calcium concentration dialysate:physiological calcium concentration dialysate
Sponsors
The third affiliated hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients with end stage renal disease, age between 18 to 75 years, male or female; 2.Maintenance peritoneal dialysis over 90 days and less than 6 months; 3.Signed written informed consent.
Exclusion criteria
Exclusion criteria: 1.Combined with hemodialysis regularly; 2.iPTH over 600pg/ml after drug treatment; 3.Have had peritonitis, exit-site infections (ESI), and tunnel infections in 1 month; 4.Prepared for renal transplantation in 2 years; 5.Malignancy,serious infection, cirrhosis, congestive heart failure, serious anemia(Hb<70g/L), serious malnutrition(Alb<25g/L); 6.Pregnancy or suckling; 7.Cannot obey the research protocol; 8.Current or recent (within 3 months) under research of other clinical trial. 9.Unsuited for the trial judged by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| iPTH control rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| iPTH;corrected serum calcium;serum phosphate;Bone alkaline phosphatase;FGF-23;vitamin D3;calcium control rate;serum phosphate control rate;Slope of residual renal GFR decline curve;The rate of iPTH above 800pg/ml after vitamin D treatment;The rate of pathologic fracture;Vascular calcification score;The carotid - femoral pulse wave velocity;Itch score;Ostalgia rate;Hospitalization rate;Mortality; | — |
Countries
China
Contacts
Public ContactHe Yani
Outcome results
None listed