Effect of scaple nerve block with ropivacaine (0.2%, 0.33%, 0.5%) on postoperative pain in patients undergoing craniotomy under general anesthesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15006030

Enrollment

Unknown

Registered

2014-11-26

Start date

2015-02-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain after craniotomy

Interventions

0.2% ropivacaine study group:scaple nerve block with 0.2%ropivacaine 8ml

0.33% ropivacaine study group:scaple nerve block with 0.33%ropivacaine 8ml

0.5% ropivacaine study group:scaple nerve block with 0.5%ropivacaine 8ml

control group:blank control

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Female or male, and any race, to be aged from 18 to 60 years at the screening visite; 2. Scheduled to undergo craniotomy under general anesthesia; 3. Patients with ASA I and II; 4. Body mass index (BMI) >/=18kg/m2 and </=30kg/m2.

Exclusion criteria

Exclusion criteria: 1. Inability to understand and use the visual analog scale (VAS); 2. Proven or suspected allergy to local anesthetics; 3. Proven coagulation disorders; 4. The incision is beyond the scope of scalp nerve block.

Design outcomes

Primary

Measure	Time frame
VAS pain scores at postoperative hours 2, 4, 6,24;	—

Secondary

Measure	Time frame
Total postoperative consumption of narcotic analgesic,in mg,of through 24 hours;Time to first postoperative use of supplementary analgesic medication;Dizziness, postoperative respiratory depression, itchy skin and related local anesthetics poisoning;Perioperative basic vital signs;	—

Countries

China

Contacts

Public ContactLi Yu

biaojieli@tom.com+86 18980601545

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026