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Effects of vildagliptin combined with insulin on the daily acute glucose fluctuations by continuous subcutaneous glucose monitoring in patients with type 1 diabetes compared with conventional insulin therapy

Effects of vildagliptin combined with insulin on the daily acute glucose fluctuations by continuous subcutaneous glucose monitoring in patients with type 1 diabetes compared with conventional insulin therapy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15005986
Enrollment
Unknown
Registered
2015-02-12
Start date
2014-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 1 diabetes

Interventions

vildagliptin+intensive insulin therepy group:vildagliptin 50mg bid+conventional intensive insulin therepy
conventional insulin therapy group:conventional insulin therapy

Sponsors

Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 30 Years

Inclusion criteria

Inclusion criteria: Patients were eligible to participate in the study if they were 14-30 years old, had documented Type 1 diabetes, male or female, fasting C peptide level less than or equal to 200 pmol/L, glutamic acid decarboxylase antibody (GAD) level >7.5U/mL.

Exclusion criteria

Exclusion criteria: gestational diabetes, special type diabetes, pregnancy diabetes, pregnant women, secondary diabetes, T1DM with the complications of heart, liver, kidney and other important organs disease.

Design outcomes

Primary

MeasureTime frame
daily acute glucose fluctuations;—

Secondary

MeasureTime frame
HbA1c;area under the curve of C peptide (AUCC);the dosage of insulin;—

Countries

China

Contacts

Public ContactYuan Fengyi
aixixi1860@126.com+86 13392683068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026