lung cancet
Conditions
Interventions
Extending the time of treatment group:Aprepitant giving by extending the schedual
Routine group:Aprepitant giving by routine schedual
control group:No
Sponsors
Cancer Center, West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. pathologically diagnosed lung cancer patients( including NSCLC and SCLC) 2. age between 18 to 75 3. first time receiving chemotherapy, chemotherapy plan is cisplatinum united one of the following medicine: paclitaxel, gemcitabine, vinorelbine, pemetrexed, etoposide, irinotecan. 4. receiving 3-day cisplatin chemotherapy regimen; 5. has no radiotherapy or targeted therapy plan (except endostar) within 21 days after first cycle chemotherapy; 6. No gastrointestinal tract metastasis, no brain metastasis; 7. No chronic digestive tract disease history, no chronic nauseas or vomits disease history( such as vertigo, Meniere's Syndrome); 8. Hematology, hepatorenal function and critical viscera index meet chemotherapy requirements.
Exclusion criteria
Exclusion criteria: 1. use to have systemic chemotherapy; 2. still not controlled cancer pain, need cancer pain titration or adjust opiates analgesics or still not perfectly controlled opiates medicine’s digestive tract reaction; 3. Patients must have had no nausea or vomiting for 3 days before study entry; 4. got active digestive tract ulcer or gastrointestinal bleeding history in past one year; 5. cannot read or independently accomplish the questionnaire; 6. cannot oral administrate medicine; 7. Poor compliant patients, participated cannot accomplish research as planed patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the proportion of patients with complete response;frequence of emergency use anti-vomit medicine;adverse events;Influence of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of without nauseas; | — |
Countries
China
Contacts
Public ContactLi Yanying
Outcome results
None listed