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The effect of preemptive analgesia on the fast-track surgery of colon carcinoma

The effect of preemptive analgesia on the fast-track surgery of colon carcinoma

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15005931
Enrollment
Unknown
Registered
2015-02-03
Start date
2015-02-09
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colon carcinoma

Interventions

open colectomy withpreemptive analgesia :1.20 minutes befor the operation, intravenous inject with 10mg dexamethasone, 100mg FlurbiprofenAxetil. 2. preincision, inject with 8ml 0.5%levobupivacaine in
open colectomy witha patient-controlled analgesia:After open colectomy, give the patient a patient-controlled analgesia pump. apatient-controlled analgesia pump contain 200ug sufentanil, 5mg Dezocine,
Laparoscopy with a patient-controlled analgesia pu:After laparoscopy, give the patient a patient-controlled analgesia pump. apatient-controlled analgesia pump contain 200ug sufentanil, 5mg Dezocine, 3

Sponsors

Department of Digestive Surgery, Xijing Hospital of Digestive Diseases, the Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. age: 18-75; 2. selectivecolon carcinoma operation; 3. subjects accept the trail and sign informed consent

Exclusion criteria

Exclusion criteria: 1. emergency operation in 12 hours after hospitalization; 2. possible or definitive infection around the incision; 3. usedexamethasone, FlurbiprofenAxetil, levobupivacaine, Celecoxibbefor operation; 4. diabetes; 5. ASA >=4; 6. chronic pain patients, no carcinomatous pain. Hyperalgesi, hypalgesia; 7. nervous system diseases or consciousness disorders; 8. pregnant woman or lactation.

Design outcomes

Primary

MeasureTime frame
Total hospital stay;

Secondary

MeasureTime frame
fast-track index;VAS pain index;stress reaction index;anesthesia index;incidence of complication;

Countries

China

Contacts

Public ContactZhao Qinchuan
zhaoqc@fmmu.edu.cn+86 13809153899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026