Chronic gastritis
Conditions
Interventions
A1:Chinese Herb decoction+powder1
A2:Chinese Herb decoction+powder2
Control:Almagate
Sponsors
Xiyuan Hospital Affiliated to China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet diagnostic criteria of chronic atrophic gastritis; 2. To be aged 18-70 years old; 3. over grade ?gastric erosions, with erythema or mucosal bleeding 4. with any symptom of early satiation, postprandial fullness, epigastric pain, epigastric burning; 5. sign the informed consent and will accept the corresponding treatment.
Exclusion criteria
Exclusion criteria: 1. Patients with Helicobacter pylori infection; 2. Patients with chronic atrophic gastritis accompany with severe dysplasia, upper gastrointestinal hemorrhage peptic ulcer, gastroenteric tumor; 3. Patients with Gastrointestinal organic diseases(such as chronic pancreatitis, hepatic cirrhosis,etc) or systemic diseases which can affect gastrointestinal power(such as hyperthyroidism?diabetes mellitus, chronic renal insufficiency, mental diseases and nerve system diseases etc); 4. Patients with severe heart, hepatic, renal diseases, hematopoietic diseases, and tumor; 5. except the study drugs, patients need to use the drugs which will affect the gastrointestinal function(such as H2RA, PPI, gastric mucosa protectant, acid-inhibitory drugs, prokinetic agents, anticholinergic drugs, etc. or have similar effect of traditional Chinese medicine; 6. With drinking history in nearly a week; 7. Pregnant and Lactating women; 8. With the history of mental or nerve system diseases; 9. With the history of allergic reaction to used drugs; 10. Patients who have participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The improvement of the gastric mucosal erosion under gastroscope;The improvement of histopathology presentations of Acute and chronic inflammation and atrophy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom score;Patients Report Outcomes score;Safety index; | — |
Countries
China
Contacts
Public ContactTang Xudong
Outcome results
None listed