Tranexamic acid used in joint replacement operation in perioperative period
Conditions
Interventions
The local use of tranexamic acid group :The local use of tranexamic acid
Tranexamic acid group with vein:Tranexamic acid with vein
Sponsors
People's Hospital of Karamay City, Xinjiang
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient younger than 80 years old; No cognitive impairment, communication difficulties or mental and neurological diseases; No alcohol or drug dependence syndrome; no morphine or local anesthetic allergy history; for the non steroidal anti-inflammatory drug allergy history; No liver and kidney dysfunction and coagulation dysfunction; No history of peptic ulcer disease and hemorrhagic disease history; Preoperative Hgb, PLT, blood coagulation function were normal; Preoperative double lower limb venous ultrasound showed no abnormalities; The patients were informed consent, and approval from the hospital ethics committee.
Exclusion criteria
Exclusion criteria: 1) had had a previous DVT; 2) use TXA taboo: including the tendency of thrombosis in patients with atrial fibrillation, stent implantation, patients with pacemaker implantation patients; 3) blood coagulation function disorder; combined with severe coagulopathy, active gastric ulcer or are receiving anticoagulant treatment in patients with; 4) TXA allergy; 5) serious heart, lung, liver, renal insufficiency patients; Body mass index; 6) body mass index (BMI) is greater than 35; 7) bilateral knee OA or undergoing knee artificial revision arthroplasty patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood loss;Hb; | — |
Countries
China
Contacts
Public ContactYue Yong
Outcome results
None listed