colorectal cancer
Conditions
Interventions
Trial group :Cinobufotalin combination chemotherapy
Sponsors
Putuo Hospital , Shanghai University of Tranditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Volunteered to participate in this study and signed an informed consent form; 2. There is a clear pathological diagnosis of colorectal cancer; 3. TMN staging Phase III or IV; 4. Patients after radical surgery 5. Patients had no other chemotherapy or radiotherapy 6. Age arrange from 18 to 80 years old, no sex limit; 7. Karnofsky score more than 70 points. 8. no serious disorders in heart, liver, kidney, and hematopoietic system, chemotherapy contraindications, and other drug evaluation factors.
Exclusion criteria
Exclusion criteria: 1. Do not meet the inclusion criteria above; 2. Patients had been chemotherapy or radiotherapy; 3. The patients with abdominal or hepatic recurrence or metastasis; 4. Significant heart (history of severe heart disease, such as coronary heart disease, myocardial infarction and so on), liver (ALT, AST has obvious abnormalities), kidney (CKD stage more than 2) or other function damage, mentally ill, pregnant or lactating women; 5. Allergies or multiple drug allergies; 6. Patients participated in other clinical trials,before the trial three months ago.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| routine blood test;Urine routine test;Fecal routine test;Fecal occult blood;Liver and kidney function;Immune functionCD3?CD4;Tumor markers CA199, CEA, CA50, CA125;TCM Syndrome Rating Scale;Piper Fatigue Scale; | — |
Contacts
Public ContactTeng Chen
Outcome results
None listed