The effects and mechanism of statins on Glucose metabolism in elderly patients with atherosclerotic cardiovascular disease

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-15005761

Enrollment

Unknown

Registered

2015-01-03

Start date

2015-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerotic cardiovascular disease

Interventions

Atorvastatin calcium nondiabetic group:Atorvastatin calcium

Atorvastatin calcium diabetic group:Atorvastatin calcium

Rosuvastatin calcium nondiabetic group:Rosuvastatin calcium

Rosuvastatin calcium diabetic group:Rosuvastatin calcium

Pitavastatin calcium nondiabetic group:Pitavastatin calcium

Pitavastatin calcium diabetic group:Pitavastatin calcium

Eligibility

Sex/Gender

All

Age

75 Years to 100 Years

Inclusion criteria

Inclusion criteria: Older than 75 years old, diagnosed as elderly patients with atherosclerotic cardiovascular disease (including simultaneous diagnosed as type 2 diabetes and non-diabetic patients). Subjects must have signed an informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study; alcohol and tobacco were not allowed during the trial.

Exclusion criteria

Exclusion criteria: Potential subjects who meet any of the following criteria will be excluded from participating in the study: Severe liver and kidney dysfunction, or who had Severe muscle pain or abnormal liver function after taking statins.

Design outcomes

Primary

Measure	Time frame
Gene HDAC3;glucose;Plasma insulin;Liver function;Myocardial enzymes;	—

Countries

China

Contacts

Public ContactZhu Jianyou

jianyouzhu90@163.com+86 18815316211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026