cerebral palsy
Conditions
Interventions
Botulinum toxin A injection group:Botulinum toxin A inject plus physical therapy
Physical therapy group :Physical therapy
Typically developing children:No
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. diagnosis of spastic cerebral palsy according to clinical criteria; 2. minimum age of 2 years old and maximum age of 18 years old; 3. The participants with spastic CP were classified at level I to V of the Gross Motor Function Classification System (GMFCS); 4. had not undergone botulinum toxin treatment in previous 6 months; 5. not had a history of lower limb surgery; 6. Parents can accept the content of the consent form and they agree to sign it.
Exclusion criteria
Exclusion criteria: 1. any health problems that are not associated with cerebral palsy, uncontrolled seizures; 2. contractures that limited the ankle joint motion;received orthopaedic surgery in the lower limb before this study or who want to receive it within the period of study; 3. received botulinum toxin injection in the lower limb during the last 6 months before this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The calf circumference;Leg length;Gastrocnemius muscle fascicle length;Gastrocnemius muscle volume;Gastrocnemius muscle pennation angle;Gastrocnemius muscle thickness;Tibialis anterior muscle fascicle length;Tibialis anterior muscle volume;Tibialis anterior muscle pennation angle;Tibialis anterior muscle thickness;Tibialis anterior muscle physiological cross-sectional area;Gastrocnemius muscle physiological cross-sectional area;soleus muscle physiological cross-sectional area;soleus muscle fascicle length;soleus muscle volume;soleus muscle pennation angle;soleus muscle thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| MAS;Modified Tardieu scale;PRS;ADL;GMFM;GMFCS;PROM;Weight;Height; | — |
Countries
China
Contacts
Public ContactKaishou Xu
Outcome results
None listed