The application of dexmedetomidine combined with creatine phosphate sodium in patients undergoing surgical evacuation of the intracranial hemorrhage and cardiopulmonary bypass

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-14005656

Enrollment

Unknown

Registered

2014-12-11

Start date

2014-12-31

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial hemorrhage/ heart disease

Interventions

Group TD:Group TD receive DEX (40ug/ml) 0.6ug/kg for 10 min, then change into 0.4ug/kg/h

Group TA:Group TA receive 1g/100ml creatine phosphate sodium

Group TDA:Group TDA receive DEX (40ug/ml) 0.6ug/kg for 10 min, then change into 0.4ug/kg/h and 1g/100ml creatine phosphate sodium

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-70 years; 2. ASA I-IV.

Exclusion criteria

Exclusion criteria: 1. Coagulopathy; 2. history of drug allergy; 3. Hypertension; 4. Liver and kidney dysfunction.

Design outcomes

Primary

Measure	Time frame
SBP, DBP, HR;GCS, Glasgow Coma Scale;the flow of drainage bag;	—

Secondary

Measure	Time frame
IL-6;IL-8;IL-10;TNF;MDA;SOD;4-HNE;NT;8-OHDG;	—

Countries

China

Contacts

Public ContactLI JUAN

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026