postoperative pain
Conditions
Interventions
Control Group:patient controlled analgesia:morphine 0.5mg/ml, background infusion time 1ml/h, block time 6min, single bolus 2ml
Trial Group:patient controlled analgesia:morphine 0.5mg/ml+dexmeditomidate 2ug/ml, background infusion time 1ml/h, block time 6min, single bolus 2ml
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. patients who undertake selective major surgery; 2. age between 60 and 85 years-old.
Exclusion criteria
Exclusion criteria: 1. History of mental disease; 2. history of sick sinus syndrom; 3. bradycadia (HR less than 50bpm); 4. II or III AVB; 5. severe hepatic disease (more than Child-Pugh C); 6. severe renal disease (dialysis); 7. body weight less than 50Kg
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative consumption of morphine; | — |
Countries
China
Contacts
Public ContactWang Dongxin
Outcome results
None listed